Isaac Newton – One Bad Apple

Isaac Newton is one of the most well known historical figures in the world of physics, and rightfully so. As the father of classical mechanics, Newton has many discoveries to his name. He was the first falling apple victim to understand the gravity of the situation; he got things moving in classical physics with his laws of motion; he shed some light on the mysteries of, well, light. Many people know him for his vast contributions to our understanding of the natural world, and Newton’s ideas were so significant that he even became president of the Royal Society, a prestigious group of scientists with a strong influence on the European scientific community during his time.

However, despite all his achievements, Newton was not the best role model. For a man who talks a lot about standing on the shoulders of giants, he sure had a chip on his own. Newton was a vain and vindictive individual who would often take advantage of his influence in order to punish those who got in his way. Today, we’ll be looking at three such cases of famous scientists whose lives were screwed over by the force of just one Newton.

Victim 1: Robert Hooke

Perhaps the most famous of Newton’s disputes was his rivalry with Robert Hooke (you may know him from Hooke’s law). The conflict between the two scientists began when Newton was at an early stage in his scientific career. Before Newton rose to power, Hooke was one of the most influential physicists of his time, so when Newton presented his findings to the Royal Society, it was Hooke whom he had to impress.

One of Newton’s early contributions to science was his theory on the properties of light and how light, Newton thought, consisted of particles. But Hooke and many other physicists at the time were supporters of the wave theory of light, so when Newton shared his ideas with the Royal Society, he was faced with admonishment from Hooke. As one could imagine, Newton did not take criticism lightly, and he held a grudge against Hooke for a long time. Over the years, the two physicists disputed over many things, such as who deserved credit for the concept of gravity, until Hooke’s death in 1703, coincidentally the same year that Isaac Newton became Royal Society president. According to an apocryphal story, Newton even kept his grudge after his rival died and gave orders to have the only painting of Hooke destroyed in an attempt to bury his legacy.

Note: This portrait was made centuries after Hooke’s death based on historical accounts of his appearance

Victim 2: Gottfried Wilhelm Leibniz

Who was the inventor of calculus? If your answer was Newton, you’d be correct. But if you thought it was Gottfried Wilhelm Leibniz, you aren’t wrong either. Today, the general consensus is that these two men both invented calculus on their own, but in the late 17th century, the topic was one of much debate among the scientific community.

While it is true that Newton invented calculus first, to maintain his reputation as an incredible genius, Newton had a knack for publishing his discoveries while concealing the ways in which he made them. This worked well for Newton until Leibniz independently discovered the same mathematical techniques Newton used to construct his theories and decided to share them with the rest of the world. Of course, when his techniques were no longer secret, Newton wanted all the credit for inventing calculus to himself and began a public dispute over the matter with Leibniz.

There were supporters on both sides of the debate, but Leibniz never stood a chance against Newton’s unmatched determination. In secret, Newton pumped out article after article in defense of himself and disguised them as writings from his friends, and eventually, the debate boiled down to the decision of the Royal Society, where Newton had the upper hand, of course. As the Society’s president, Newton organized a biased committee to investigate the matter. Ultimately, not only did the committee rule in favor of Newton, but it also accused Leibniz’s work of being derivative (pun very intended) and that Leibniz had plagiarized Newton’s ideas. Even up until his death, Leibniz never got the positive recognition he deserved. But at least today, outside of physics circles, Leibniz’s calculus notation is still the most widely used.

Victim 3: John Flamsteed

John Flamsteed, the Astronomer Royal, was another victim of Newton’s vitriol. As head of the Royal Observatory, Flamsteed spent much of his time looking at celestial objects and was known for keeping a meticulous record of his observations. In fact, Newton used Flamsteed’s observational data to help him write his original magnum opus, the Principia Mathematica, in which he described the foundations of classical mechanics. However, between Newton’s publication of the first edition of Principia and his venture into writing the second edition, things became sour between the two scientists. According to Flamsteed, Newton never showed him any signs of appreciation or respect despite his contributions to Newton’s work. He even accused Newton of publishing some of his findings without his permission. As such, Flamsteed was intent on denying Newton access to anymore data for his research.

However, in classic Newton fashion, in an attempt to obtain the data he needed, he used his authority as president of the Royal Society to forcefully take Flamsteed’s data and have it published by Flamsteed’s biggest rival, Edmond Halley. Luckily, in response, Flamsteed took Newton to court and had Newton’s actions nullified before any damage was done, and out of spite, Newton never acknowledged Flamsteed’s contributions to his theories ever again.

As you can see, Isaac Newton is a textbook example of why you should never meet your heroes. From framing Leibniz while he was alive to ensuring Hooke was unframed after death, Newton was one bad apple who gave other scientists a headache. And of course, Newton isn’t the only one. With just a little digging, you’d find that physics has quite a few other problematic big shots, and maybe those can be articles for another time. But as they say in the phys-biz, every quark has its quirk (I just made that up, but I hope it’ll catch on). What’s important is separating the physics from the physicist.

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  Timothy Durham was convicted of rape when a test showed his DNA genotype matched the DNA recovered from the crime scene. Eye witnesses testified that Durham was in a different state at the time of the incident, but he wasn’t exonerated from his 3000 year sentence until follow up DNA analysis showed that the preliminary forensic analysis used in the trial was misinterpreted (Thomas et al.). DNA testing serves an invaluable part in our criminal justice system, but it comes with complications and bias that can lead to wrongful convictions and misinformed juries.  

Background:

Forensic genetics aims to identify the origin of a biological sample. It can be traced back to Karl Landsteiner who discovered human ABO blood groups. With blood groups, suspects could be eliminated based on their blood type. For example, if a suspect had type A blood and there was type B blood left at the scene by the perpetrator, the investigators could rule out the suspect. Unfortunately, the reverse didn’t work. If the suspect and perpetrator both had the same blood type, it can’t be concluded that the suspect was guilty. Blood identifiers evolved into 8 distinct categories which improved the ability to eliminate suspects, but could only conclude that (if the system matched) it might be the perpetrator or this person might be related to the perpetrator (Jobling and Gill). The field evolved in the 1980s with the discovery of Minisatellites, lines of repetitive DNA that don’t encode proteins. Minisatellite patterns in DNA create what we know today as the DNA fingerprint, and it has a much higher accuracy rate than previous methods (Augustyn et al.). Around the same time, a breakthrough for victims of sexual assault was discovered. In the case of assault, bodily fluids of both the victim and the assaulter can get mixed. A process called differential lysis was created which could selectively increase the concentration of sperm in a fluid sample thereby allowing for accurate DNA testing (Jobling and Gill). Forensics evolved to use single-locus probe testing after several years because of its ease of interpretation. It looked at specific minisatellites that had high variability between subjects. This was the first DNA-based method to be used in a criminal investigation. Two murder homicides from several years apart were connected using DNA evidence. The evidence was then used to exonerate an innocent man, and the guilty party was found when he tried to evade mandatory DNA testing for all men in the small town. His guilt was then reinforced when the DNA profiles matched, and he gave a confession (Jobling and Gill). Finding DNA at a crime scene doesn’t guarantee that you’ll find a murderer. There are issues with non-pure samples and limited samples that make DNA work difficult, and accreditation of facilities and new techniques and take time (Jobling and Gill).  

Subjectivity of DNA Interpretation:

In a 2009 publication, the National Academy of Science discusses the possibility for subjective influence in lab based forensics. The interpretation bias happens in complex cases where, for example, there could be a mixture of DNA. A study published in 2011 looked specifically at this issue. A gang rape happened in Georgia, and the mixture in DNA from the case was used to prosecute one suspect after another suspect took a plea bargain to testify against him. With DNA mixtures, there are three possible conclusions: suspect excluded, suspect cannot be excluded, and inconclusive. If the suspect is excluded, it means that there’s little to no possibility that his DNA is part of the sample. If the suspect cannot be excluded, it means that there’s a possibility that his DNA is part of the sample. In the trial, the DNA examiners who knew the context of the case concluded that the suspect being prosecuted could not be excluded. The 2011 study gave the DNA evidence from this case and the DNA profiles of the suspects to 17 forensic examiners. These examiners had no context of the case, and they all worked independently. Of the 17, only 1 came to the same conclusion (suspect cannot be excluded) as the examiners who knew the context of the case. Twelve of the 17 concluded that the suspect who was prosecuted and convicted had no relation to the DNA found in the sample. Not only does this show that subjectivity occurs due to the context of the case, but the 17 examiners came up with different findings based on their past experiences meaning that not all DNA analysis is objective. Some organizations like the Scientific Working Group on DNA Analysis Methods say that quantitative statistical evidence should be presented with every categorical conclusion, but the US doesn’t require this (Dror and Hampikian).

False Positives:

There are two categories that cause wrongful identification in a DNA report: coincidental matches and false positives. Coincidental matches are DNA matches between two unrelated people. The probability of these matches is about 1 to 500,000 for white individuals and about 1 to 350,000 for black individuals. This small probability of coincidental matches makes people feel confident in DNA evidence. False positives, on the other hand, are matches between DNA and test DNA that result from issues in the forensics lab. There have been multiple cases of forensics labs accidentally switching victim and suspected rapist DNA which lead to convictions that were later overturned when the lab realized the error. There are also cases of misreading or misunderstanding a sample. In a case from 1993, a man was convicted of rape because someone interpreted a mixed sample of victim and perpetrator DNA as an individual sample. The conviction was again overturned. To prevent false convictions, retesting DNA is allowed, but it’s not an efficient solution. Many people are pushing for statistical information on the probability of false positives, so that the jurors can make accurate judgements based on DNA evidence (Thomas et al.).  

Conclusion:

DNA analysis is a useful tool for the criminal justice system, but subjectivity can be an issue in forensic testing. To combat wrongful convictions, there are organizations like The Innocence Project who use DNA testing to free the innocent, but reformed forensic testing standards should be put in place to prevent subjectivity and to ensure juries are correctly informed during trials. https://www.innocenceproject.org/    

Citation:

Augustyn , Adam, et al. “DNA Finerprinting.” Encyclopedia Britannica , 26 Apr. 2018, www.britannica.com/science/DNA-fingerprinting#ref153186. Dror, Itiel E., and Greg Hampikian. “Subjectivity and Bias in Forensic DNA Mixture Interpretation.” Science & Justice, vol. 51, no. 4, 2011, pp. 204–208., doi:10.1016/j.scijus.2011.08.004. Jobling, Mark A., and Peter Gill. “Encoded Evidence: DNA in Forensic Analysis.” Nature Reviews: Genetics, vol. 5, no. 10, Oct. 2004, pp. 739–751., doi:10.1038/nrg1455. Thompson, William C, et al. “How the Probability of a False Positive Affects the Value of DNA Evidence.” Journal of Forensic Sciences, vol. 48, no. 1, Jan. 2003, pp. 1–8., doi:10.1520/jfs2001171.