Beats to Cellularly Divide To

When it comes to learning key biological concepts, it can be helpful to connect new material to something you’re familiar with or passionate about. In this vein, I chose to put together a short playlist that draws parallels between popular songs and the phases of mitosis by assigning each phase of mitosis to a song on the playlist. Linking this biological process with music can serve as a learning tool to help deepen a student’s understanding and memory of the cellular division process. With that said, here is my list of “Beats to Cellularly Divide To”:

  1. Prophase: Pompeii by Bastille

This alternative song conjures a vivid image in the listener’s mind of the disruption caused to civilization by the volcanic eruption at Pompeii. Indeed, prophase can be thought of in a similar vein: it begins the resource-intensive process of mitosis, which will ultimately result in two daughter cells. The lyric “And the walls kept tumbling down in the city that we love” is particularly on the nose, as the nuclear envelope (analogous to the “walls” described in this lyric) disappears during prophase, as cellular division begins.  

  1. Metaphase: The Middle by Grey, Maren Morris, and Zedd

This classic pop tune reiterates the phrase “why don’t you just meet me in the middle?”, the same sentiment reflected by the second phase of mitosis: metaphase. During this part of mitosis, the chromosomes align at the metaphase plate near the center of the cell, forming a line. Just like the song describes how you may want a friend to ‘meet you in the middle’ during a time of conflict, the chromosomes similarly meet in the middle during the second phase of mitosis. 

  1. Anaphase: Drift Away by Uncle Cracker

“Drift Away” is a rock song which describes the feeling of enjoying a piece of music so much you seem to get lost in it, or ‘drift away’ from reality. In a similar manner, anaphase involves the separation of sister chromatids as they are pulled apart by kinetochore fibers, ‘drifting away’ from each other to opposite sides of the cell. 

  1. Telophase: We Are Never Ever Getting Back Together by Taylor Swift

This Taylor Swift song describes a break-up, boldly declaring “We are never, evеr, ever gettin’ back togеther”. This aligns with the aims of telophase, as this stage of mitosis involves the cell permanently splitting into two new daughter cells. Reformation of the nuclear membrane takes place, and nucleoli reappear and remain in each of the two new cells. Both cells now contain a complete copy of the original cell’s genome. Thus, they are completely separate and ready to exist apart, similar to the speaker in the song “We Are Never Ever Getting Back Together” post-breakup. 

This concludes my “Beats to Cellularly Divide To”. My hope is that this playlist can serve as a learning tool to help would-be students comprehend and remember the phases of mitosis and the process of cellular division. It also serves as a fun way to musically engage with the sciences. The full playlist can be found on Spotify at this link: https://spotify.link/0NoUZST4JIb. Happy listening!

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